Restoration of Aerial Mycelium and Antibiotic Production in a Streptomyces griseoflavus Arginine Auxotroph
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چکیده
منابع مشابه
Restoration of aerial mycelium and antibiotic production in a Streptomyces griseoflavus arginine auxotroph.
An arginine auxotrophic mutant was obtained from Streptomyces griseoflavus (bicozamycin-producing strain). The mutant grew on synthetic agar supplemented with either arginine, ornithine, citrulline or argininosuccinate, but produced massive aerial mycelium and bicozamycin only with citrulline. In liquid culture, citrulline also completely restored the ability of the mutant to produce bicozamyci...
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We have extensively purified a factor from conditioned medium that restores aerial mycelium formation to a mutant of Streptomyces coelicolor that is defective in morphological differentiation. Response to this factor is shown to depend on the presence of the BldK oligopeptide import system. We suggest that this substance acts at the first step in a putative cascade of developmental regulatory s...
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accelerated aerial mycelium formation in various actinomycete species, including S. alboniger. This induction was completely inhibited by ethylene glycol bis(/?-aminoethylether)-JV,N,N ',N '-tetraacetic acid (EGTA), a Ca2+-specific chelating agent. Ca2+ thus has been shown to play a role in aerial mycelium formation of 21 (58%) out of 36 strains of actinomycetes tested3). Ca2+ is known as a sec...
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Despite the fact that most industrial processes for secondary metabolite production are performed with submerged cultures, a reliable developmental model for Streptomyces under these culture conditions is lacking. With the exception of a few species which sporulate under these conditions, it is assumed that no morphological differentiation processes take place. In this work, we describe new dev...
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BACKGROUND AND OBJECTIVES Proteases are a group of enzymes that catalyze the degradation of proteins resulting in the production of their amino acid constituents. They are the most important group of industrial enzymes which account for about 60% of total enzymes in the market and produced mainly by microorganisms. The attempts were made to study the kinetic parameters of protease produced by S...
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ژورنال
عنوان ژورنال: Microbiology
سال: 1984
ISSN: 1350-0872,1465-2080
DOI: 10.1099/00221287-130-8-2007